Executive Order

The Genesis Mission

A national effort to unleash a new age of AI-accelerated innovation.


We are in a race for global technology dominance. To accelerate scientific advancement, the White House creates the Genesis Mission—a historic national effort comparable in ambition to the Manhattan Project.

By combining the world's largest collection of Federal scientific datasets with high-performance computing, we will train foundation models to test hypotheses, automate workflows, and secure America's future.

The American Science and Security Platform

The Secretary of Energy is directed to establish a unified infrastructure platform providing:

  • Supercomputing Resources: Access to DOE national laboratory supercomputers and secure cloud environments.
  • AI Agents: Autonomous agents to explore design spaces and evaluate experimental outcomes.
  • Secure Datasets: Proprietary, federally curated, and open scientific datasets alongside synthetic data generation.

Execution Timeline

60 Days

Identify 20 priority science and technology challenges (e.g., Nuclear Fusion, Advanced Manufacturing).

90 Days

Identify computing, storage, and networking resources.

120 Days

Identify data assets and develop a security plan.

270 Days

Demonstrate initial operating capability of the Platform.

Priority Domains

Advanced Manufacturing
Biotechnology
Critical Materials
Nuclear Fission & Fusion
Quantum Information Science
Semiconductors
Donald J. Trump
The White House
November 24, 2025